Consortium on the Neurobiology of Adolescent Drinking in Adulthood (NADIA) Administrative Resource (Collaborative U24 - Clinical Trial Not Allowed) | RFA AA 20 004

Opportunity Information: Apply for RFA AA 20 004

The Consortium on the Neurobiology of Adolescent Drinking in Adulthood (NADIA) Administrative Resource opportunity (RFA-AA-20-004) is a National Institutes of Health cooperative agreement (U24) focused on building and sustaining a coordinated research consortium that examines how alcohol exposure during adolescence can produce lasting, measurable changes in brain development and adult behavior. The central scientific aim is to understand persistent alterations in complex brain function-behavior relationships that follow repeated alcohol exposure during the adolescent period, with an emphasis on how such exposure may disrupt typical brain maturation and influence adult abilities.

This funding mechanism is designed around a consortium model rather than isolated single-lab projects. In practice, it supports interdisciplinary, multi-institutional collaboration among established investigators who are already conducting high-quality alcohol research. The intent is to keep a cohesive set of research efforts moving forward across different sites, promoting shared approaches, coordination, and integration of findings. Because it is a cooperative agreement, the NIH (through NIAAA) is typically more actively involved than in a standard grant, with expectations for coordination, shared governance, and alignment with consortium-wide priorities.

A key boundary of the initiative is that it is limited to animal studies only. NIAAA highlights a specific interest in experimental designs that use controlled alcohol doses and defined exposure periods, which are most feasible and ethically permissible in animal models. In addition, the notice states "Clinical Trial Not Allowed," reinforcing that the supported work should not involve clinical trials and should remain in the preclinical/animal research space.

Eligibility is broad across many types of U.S.-based organizations. Eligible applicants include various levels of government (state, county, city/township, and special district governments), independent school districts, public and state-controlled institutions of higher education, private institutions of higher education, federally recognized Native American tribal governments, and tribal organizations that are not federally recognized. It also includes public housing authorities/Indian housing authorities, nonprofit organizations (both with and without 501(c)(3) status, as long as they are not institutions of higher education in those categories), for-profit organizations (other than small businesses), and small businesses. The announcement also explicitly calls out additional eligible applicant types such as Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.

At the same time, there are clear restrictions related to foreign involvement. Non-domestic (non-U.S.) entities and non-domestic components of U.S. organizations are not eligible to apply, and foreign components (as defined by NIH policy) are not allowed. In other words, the project and its supported activities must remain domestic, without foreign subcomponents.

Administratively, this opportunity is categorized as discretionary funding using the cooperative agreement instrument, and it falls under the health activity category with CFDA number 93.273. The posting lists an original closing date of 2019-12-18 and a creation date of 2019-09-23. The award ceiling and expected number of awards are not specified in the provided source text, which typically means applicants would need to consult the full funding announcement or related NIH documentation for budget limits and anticipated funding levels.

Overall, the opportunity is aimed at maintaining and strengthening a structured, multi-site animal research consortium that can tackle a complex developmental neuroscience question: how adolescent alcohol exposure can reshape brain trajectories and behavior into adulthood, and what that means mechanistically for long-term function.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Consortium on the Neurobiology of Adolescent Drinking in Adulthood (NADIA) Administrative Resource (Collaborative U24 - Clinical Trial Not Allowed)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.273.
• This funding opportunity was created on 2019-09-23.
• Applicants must submit their applications by 2019-12-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA AA 20 004

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